Azathioprine USP 50mg Tablet

About Azathioprine USP 50mg Tablet

1. Technical Specifications

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2. Product Description

Azathioprine 50mg Tablet is an immunosuppressive medication primarily used to prevent organ transplant rejection and to treat autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease (Crohns disease, ulcerative colitis), and certain skin disorders.
It works by suppressing the immune response, reducing inflammation and preventing the immune system from attacking the bodys own tissues. Azathioprine acts as a purine synthesis inhibitor, interfering with DNA replication in rapidly dividing immune cells.

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3. Product Highlights

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4. Therapeutic Uses

• Autoimmune Disorders: Rheumatoid arthritis, lupus, vasculitis, autoimmune hepatitis.

• Organ Transplantation: Prevents rejection in kidney, liver, or heart transplants.

• Inflammatory Bowel Diseases: Helps manage Crohns disease and ulcerative colitis by reducing intestinal inflammation.

• Dermatologic Conditions: Used in pemphigus vulgaris, psoriasis, and other immune-mediated skin disorders.

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5. Side Effects

Common:

• Nausea, vomiting, loss of appetite

• Mild hair loss

• Fatigue or malaise

Serious (require medical attention):

• Bone marrow suppression (low WBCs, RBCs, or platelets)

• Increased susceptibility to infections

• Liver toxicity (jaundice, elevated liver enzymes)

• Hypersensitivity reactions (fever, rash, joint pain)

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6. Precautions

• Use strictly under medical supervision; regular blood count and liver function monitoring required.

• Avoid live vaccines during treatment.

• Use with caution in patients with liver impairment or TPMT (thiopurine methyltransferase) deficiency.

• May increase risk of infections and malignancies with prolonged use.

• Pregnancy and breastfeeding: Use only if prescribed by a physician; may cause fetal harm.

• Avoid concomitant use with allopurinol unless dose adjustment is made (can increase azathioprine toxicity).

Comprehensive Immunosuppression Solution

Azathioprine USP 50mg Tablet is designed to provide essential immunosuppressive support for adults coping with autoimmune diseases or who have undergone organ transplantation. Sourced from trusted Indian manufacturers, this medicine helps control the bodys immune responses, promoting overall health and facilitating better treatment outcomes. Its consistent quality and reliable packaging make it a preferred choice among healthcare professionals and patients alike.


Accurate Dosage and Safe Storage Practices

Each tablet is to be taken as directed by a healthcare provider, ensuring optimal benefit and minimal risk of side effects. Patients are advised to keep the tablets in a cool, dry environment, away from direct sunlight, to preserve their stability and effectiveness. Strict adherence to the recommended storage and dosage guidelines supports patient safety and therapeutic efficacy.