Bortenat 3.5mg Injection
Bortenat 3.5mg Injection

Bortenat 3.5mg Injection

Price 4140.0 INR/ Pack

MOQ : 5 Packs

Bortenat 3.5mg Injection Specification

  • Drug Type
  • Injection
  • Physical Form
  • Liquid
  • Recommended For
  • Doctor
  • Dosage Guidelines
  • As per Instructions
  • Suitable For
  • Adults
  • Storage Instructions
  • Cool & Dry Place
 

Bortenat 3.5mg Injection Trade Information

  • Minimum Order Quantity
  • 5 Packs
  • Payment Terms
  • Cash in Advance (CID), Telegraphic Transfer (T/T), Cash Advance (CA)
  • Supply Ability
  • 800 Packs Per Week
  • Delivery Time
  • 6 Days
  • Sample Available
  • No
  • Sample Policy
  • If order is confirmed we will reimburse the sample cost
  • Main Export Market(s)
  • Middle East, Africa, South America, Asia, Australia, Central America, North America, Eastern Europe, Western Europe
  • Main Domestic Market
  • All India
 

About Bortenat 3.5mg Injection

1. Technical Specifications

Attribute Details
Brand Name Bortenat Injection
Generic Name Bortezomib
Strength 3.5 mg per vial
Dosage Form Lyophilized powder for solution for injection
Route of Administration Intravenous (IV) or Subcutaneous (SC)
Packaging Type Single-use vial
Medicine Type Anticancer / Antineoplastic (Proteasome Inhibitor)
Manufacturer Natco Pharma Ltd.
Distributed By Authorized distributors

2. Product Description

Bortenat 3.5 mg Injection contains Bortezomib, a reversible proteasome inhibitor that disrupts protein degradation within cells, leading to apoptosis (programmed cell death) in cancer cells.

It is mainly used in the management of multiple myeloma and mantle cell lymphoma. The injection can be administered by IV push (35 seconds) or subcutaneous injection, as directed by a healthcare professional.


3. Product Highlights

Attribute Details
Therapeutic Category Antineoplastic (Proteasome Inhibitor)
Application Area Hematologic malignancies (Multiple Myeloma, Mantle Cell Lymphoma)
Mechanism of Action Inhibits 26S proteasome accumulation of proteins apoptosis of malignant plasma cells
Administration IV push or SC injection, dose calculated on body surface area (mg/m)
Storage Conditions Store vials below 25 C; reconstituted solution must be used within stability period as per guidelines

4. Therapeutic Uses

  • Multiple Myeloma frontline and relapsed/refractory cases

  • Mantle Cell Lymphoma in patients who have received at least one prior therapy

  • Investigated in other cancers (off-label) under physician supervision


5. Side Effects

Common:

  • Fatigue, weakness

  • Nausea, vomiting, diarrhea, constipation

  • Loss of appetite, weight loss

  • Peripheral neuropathy (numbness, tingling in hands/feet)

  • Thrombocytopenia, neutropenia, anemia

  • Fever, infections

Serious / Severe:

  • Severe neuropathy (pain, loss of sensation)

  • Heart problems (congestive heart failure, arrhythmias)

  • Lung complications (acute respiratory distress, pneumonitis)

  • Liver toxicity (increased enzymes, hepatitis)

  • Tumor lysis syndrome (rare but serious)


6. Precautions

  • Bone Marrow Suppression: Monitor complete blood counts before each dose.

  • Neuropathy: Dose modification or discontinuation required in severe peripheral neuropathy.

  • Cardiac Function: Use with caution in patients with heart disease or risk of fluid overload.

  • Kidney & Liver Impairment: Dose adjustments required.

  • Pregnancy & Breastfeeding: Contraindicated potential teratogenic effects; effective contraception needed.

  • Drug Interactions: Caution with strong CYP3A4 inhibitors/inducers (e.g., ketoconazole, rifampin, phenytoin) as they may affect bortezomib metabolism.



Professional Administration & Usage

Bortenat 3.5mg Injection is recommended exclusively for adults and must be administered by qualified doctors or healthcare professionals. Follow your physicians exact dosage guidance and never self-administer. This strict administration protocol ensures both safety and effectiveness in cancer treatment.


Proper Handling & Storage

Storing Bortenat 3.5mg Injection in a cool and dry place is critical for maintaining its stable and potent form. Keep it away from direct sunlight and moisture, and ensure the storage area is secure to prevent unauthorized access or tampering.

FAQs of Bortenat 3.5mg Injection:


Q: How should Bortenat 3.5mg Injection be administered?

A: Bortenat 3.5mg Injection must be administered by a doctor or qualified healthcare professional in a clinical setting. Never attempt to inject it yourself without proper medical supervision.

Q: What is Bortenat 3.5mg Injection used for?

A: This injection is used primarily for the treatment of multiple myeloma and mantle cell lymphoma in adult patients, as determined by a prescribing doctor.

Q: When should I take my Bortenat 3.5mg Injection doses?

A: The timing and frequency of Bortenat injections are determined by your doctor based on your individual treatment plan. Adhere strictly to the schedule provided to you.

Q: Where should Bortenat 3.5mg Injection be stored?

A: Bortenat 3.5mg Injection should be stored in a cool and dry place, away from sunlight and excessive humidity, to preserve its effectiveness.

Q: What are the benefits of Bortenat 3.5mg Injection?

A: Bortenat 3.5mg Injection may help control the progression of certain cancers in adults, improving quality of life and disease management when part of a supervised treatment plan.

Q: Who should use Bortenat 3.5mg Injection?

A: This injection is suitable for adults suffering from specific cancers, as recommended and monitored by a healthcare professional.

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